Safety data sheet. GHS / OSHA HCS 2012 format, 16 sections. Issued by Epic Peptides Lab for the catalogue items listed in Section 1.

Epic Peptides Lab

Safety data sheet · solution, metered nasal spray

Epic Peptides Lab · USA

Document number: PL-SDS-176
Revision: 1.0 · 2026-10-03

Triptorelin

solution, metered nasal spray

1Identification

Product Identifier

Triptorelin

Document Number

PL-SDS-176

Catalogue Items Covered

Id
15833
Name
Triptorelin 2mg Nasal Spray
Sku
PL-TRIPTORELIN-2MG-NS

Recommended Use

Laboratory research use by trained personnel.

Restrictions On Use

Not for human or veterinary use.

Supplier / Distributor

Epic Peptides Lab, USA

Telephone

+1 (787) 468-5291

info@epicpeptideslab.com

2Hazard(s) identification

Classification: Not classified as hazardous under OSHA HCS 2012 (29 CFR 1910.1200) or UN GHS, on the basis of the supplier safety data sheets consulted.
Label Elements: No data available.
Signal Word: No data available.
Other Hazards: No data available.

3Composition / information on ingredients

Description

Sterile aqueous solution in bacteriostatic water (0.9% benzyl alcohol), supplied in a metered-dose nasal spray bottle.

Composition

Name
Triptorelin
Full
[D-Trp6]-GnRH
Cas
57773-63-4
Formula
C64H82N18O13
Conc
≤ 0.02% w/v
Qty
2 mg per bottle
Hazards
- Reproductive toxicity — Category 1B — H360
Name
Benzyl alcohol (preservative)
Full
Benzyl alcohol, antimicrobial preservative (0.9% w/v in bacteriostatic water)
Cas
100-51-6
Formula
C7H8O
Conc
0.9% w/v
Hazards
- Acute toxicity, oral — Category 4 — H302
- Acute toxicity, inhalation — Category 4 — H332
- Serious eye damage/eye irritation — Category 2A — H319
- Skin sensitisation — Category 1B — H317
Name
Water for injection
Full
Water for injection
Cas
7732-18-5
Formula
H2O
Conc
balance to 100%

4First-aid measures

First Aid Measures

Inhalation: Move the person to fresh air and keep comfortable for breathing. If breathing is difficult or symptoms persist, call a POISON CENTER or doctor.
Skin: Take off contaminated clothing. Wash the skin with plenty of soap and water. If irritation or a rash develops, get medical advice.
Eyes: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. If eye irritation persists, get medical advice.
Ingestion: Rinse mouth. Do not induce vomiting. Call a POISON CENTER or doctor if you feel unwell.
Injection: For an accidental needle-stick: wash the site with soap and water, do not squeeze, cover with a dressing and seek medical advice; report the incident according to your laboratory's sharps procedure.

Most Important Symptoms And Effects

No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.

Likely Routes Of Exposure

Inhalation of the aerosol and absorption through the nasal mucosa are the intended laboratory routes; eye contact from mis-directed spray; skin contact.

5Fire-fighting measures

Fire Fighting Information: Aqueous solution containing 0.9% benzyl alcohol; not flammable and does not support combustion.

6Accidental release measures

Spill And Clean Up Procedures: Absorb small spills with paper towel or an inert absorbent, place in a sealed container for disposal and clean the area with water and detergent.

7Handling and storage

Safe Handling: Avoid spraying toward the eyes or face. Do not share devices. Wipe the nozzle after use and keep the cap on. Wash hands after handling.
Safe Storage: Store at 2–8 °C, protected from light; do not freeze. Keep upright and capped.
Storage Temperature: 2–8 °C, protected from light; do not freeze
Incompatible Materials: None identified by Cayman

8Exposure controls / personal protection

Occupational Exposure Limits: Benzyl alcohol: no OSHA PEL, ACGIH TLV or NIOSH REL; AIHA WEEL 10 ppm (44 mg/m³) 8-h TWA. Present at 0.9%.

No occupational exposure limits have been established for the active ingredient(s).
Exposure Controls And PPE: No data available.

9Physical and chemical properties

Physical State

Liquid

Appearance

Clear, colourless to faintly yellow aqueous solution

Properties

Odor: Odourless to faint aromatic odour (benzyl alcohol)
Ph: Approximately 4.5–7.0 (bacteriostatic water, USP) unless adjusted
Melting: About 0 °C (aqueous solution)
Boiling: About 100 °C (aqueous solution)
Flash: Not flammable; aqueous solution (benzyl alcohol flash point 93–101 °C, present at 0.9%)
Vapour: As water (about 2.3 kPa at 20 °C)
Density: About 1.00–1.02 g/mL at 20 °C
Solubility: Aqueous solution; miscible with water
Logp: Not determined
Decomp: Not applicable (aqueous solution); dissolved peptide degrades on heating

10Stability and reactivity

Stability And Reactivity

Reactivity: Stable when used per specifications; no hazardous reactions known
Incompatible: None identified by Cayman (generic: strong oxidizing agents)
Decomposition: No dangerous decomposition products known (combustion: carbon oxides, nitrogen oxides)
Conditions To Avoid: Moisture (hygroscopic), heat, light; store -20 C desiccated, dark

Conditions To Avoid

Moisture (hygroscopic), heat, light; store -20 C desiccated, dark

Incompatible Materials

None identified by Cayman

11Toxicological information

Toxicological Information: Acute toxicity, oral
No data available

Acute toxicity, dermal
No data available

Acute toxicity, inhalation
No data available

Skin corrosion/irritation
No irritant effect (Cayman)

Serious eye damage/irritation
No irritating effect (Cayman)

Respiratory or skin sensitisation
No sensitizing effects known (Cayman); drug labels report rare hypersensitivity/anaphylaxis

Germ cell mutagenicity
No data available (drug label: not mutagenic in Ames/mammalian assays)

Carcinogenicity
Not listed by IARC, NTP, OSHA (drug label: pituitary adenomas in rats at high doses, a rodent-specific effect of chronic GnRH-agonist exposure)

Reproductive toxicity
Repr. 1B (H360) per ECHA notified C&L. GnRH agonist: suppresses gonadotropins and sex steroids, reversibly abolishes fertility; FDA label (Trelstar) — contraindicated in pregnancy, may cause fetal harm/pregnancy loss

STOT, single exposure
No data available

STOT, repeated exposure
No data available

Aspiration hazard
No data available
Routes Of Exposure: Inhalation of the aerosol and absorption through the nasal mucosa are the intended laboratory routes; eye contact from mis-directed spray; skin contact.
Symptoms: No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.

12Ecological information

Ecological Information: No aquatic toxicity, persistence or bioaccumulation data from suppliers. Cayman self-assessment: water hazard class 1; ChemicalBook: WGK 3 (severely hazardous to water). Endocrine-active substance — avoid release to the environment.

13Disposal considerations

Disposal Guidance: No data available.

14Transport information

Transport Classification

Note: Not regulated as a dangerous good for transport by road (DOT 49 CFR), air (IATA/ICAO) or sea (IMDG). Not a marine pollutant. Ship refrigerated or frozen as required by Section 7; the coolant (dry ice, UN 1845) is regulated when used.

15Regulatory information

Regulatory Information

Tsca: Not listed on TSCA inventory (Cayman)
Carcinogen Listings: Not listed by IARC, NTP, OSHA, EPA
Dea: Not a controlled substance
Other: FDA-approved prescription drug substance (Trelstar/Triptodur); research-use disclaimer required. SARA 313: not listed. Transport: not regulated. ECHA C&L inventory carries notified Repr. 1B. WADA remark: named in S2.2 (gonadotropin releasing factors — buserelin, deslorelin, gonadorelin, goserelin, leuprorelin, nafarelin, triptorelin), prohibited in males.

Carcinogen Listings

No data available.

16Other information

Revision: October 3, 2026
Sources Consulted: Cayman Chemical

ECHA C&L inventory notified classifications

ChemicalBook

Selleck Chemicals

Sigma-Aldrich

Sigma-Aldrich / Supelco

MilliporeSigma

Sigma-Aldrich BVBA

Aldrich

American Regent - Sterile Water for Injection, USP

Hospira/Pfizer - Bacteriostatic Water for Injection
Confidence: medium
Additional Information: GnRH agonist (D-Trp6 analogue).

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