Safety data sheet. GHS / OSHA HCS 2012 format, 16 sections. Issued by Epic Peptides Lab for the catalogue items listed in Section 1.

Epic Peptides Lab

Safety data sheet · lyophilized powder, vial

Epic Peptides Lab · USA

Document number
PL-SDS-127
Revision
1.0 · 2026-10-03

PEG-MGF

lyophilized powder, vial

1Identification

Product Identifier
PEG-MGF
Document Number
PL-SDS-127
Catalogue Items Covered
  • Id
    2009
    Name
    PEG-MGF (Mechano Growth Factor) 2mg
    Sku
    PL-PEGMGF-2MG-VIAL
Recommended Use
Laboratory research use by trained personnel.
Restrictions On Use
Not for human or veterinary use.
Supplier / Distributor
Epic Peptides Lab, USA
Telephone
+1 (787) 468-5291
Email
info@epicpeptideslab.com

2Hazard(s) identification

Classification
Not classified as hazardous under OSHA HCS 2012 (29 CFR 1910.1200) or UN GHS, on the basis of the supplier safety data sheets consulted.
Label Elements
No data available.
Signal Word
No data available.
Other Hazards
No data available.

3Composition / information on ingredients

Description
Lyophilized (freeze-dried) powder or cake in a sealed glass vial with a rubber stopper and aluminium crimp cap.
Composition
  • Name
    PEG-MGF
    Full
    PEGylated mechano growth factor: the IGF-1Ec E-domain 24-mer carrying a polydisperse PEG
    Cas
    Not assigned
    Formula
    C121H200N42O39 (core 24-mer before PEGylation)
    Conc
    ≥ 95% (dry basis, as supplied)
    Qty
    2 mg per vial

4First-aid measures

First Aid Measures
Inhalation
Move the person to fresh air and keep comfortable for breathing. If breathing is difficult or symptoms persist, call a POISON CENTER or doctor.
Skin
Take off contaminated clothing. Wash the skin with plenty of soap and water. If irritation or a rash develops, get medical advice.
Eyes
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. If eye irritation persists, get medical advice.
Ingestion
Rinse mouth. Do not induce vomiting. Call a POISON CENTER or doctor if you feel unwell.
Most Important Symptoms And Effects
No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.
Likely Routes Of Exposure
Inhalation of dust, skin and eye contact when the vial is opened or the powder is weighed; ingestion through contaminated hands; accidental injection when reconstituted solutions are drawn into syringes.

5Fire-fighting measures

Fire Fighting Information
Combustible organic solid; finely divided powder may form dust clouds. Not flammable in the quantities supplied.

6Accidental release measures

Spill And Clean Up Procedures
Avoid dust formation. Dampen spilled powder with water, wipe up with absorbent material, place in a sealed container for disposal and clean the area with water and detergent.

7Handling and storage

Safe Handling
Open vials only in a clean area. Avoid generating or inhaling dust; weigh or reconstitute inside a ventilated enclosure when the full contents are handled as a dry powder. Reconstitute by adding diluent slowly to the vial wall; do not shake. Wash hands after handling.
Safe Storage
Store the sealed vial at the temperature stated in Section 9 (typically −20 °C for peptides, 2–8 °C for proteins), desiccated and protected from light. Allow the vial to reach room temperature before opening to avoid condensation. Reconstituted solutions: 2–8 °C, protected from light; use within the period established by your laboratory.
Storage Temperature
−20 °C (sealed vial), desiccated and protected from light; 2–8 °C acceptable for short periods
Incompatible Materials
Strong oxidizing agents; strong acids/bases.

8Exposure controls / personal protection

Occupational Exposure Limits
No data available.
Exposure Controls And PPE
No data available.

9Physical and chemical properties

Physical State
Solid
Appearance
White to off-white lyophilized powder
Properties
Odor
Expected odorless/characteristic (no SDS)
Ph
Not applicable (solid); aqueous solutions typically pH 4–7
Melting
Undetermined / not applicable (PEG conjugate, amorphous)
Boiling
Not applicable
Flash
Not applicable (non-flammable solid); combustible organic material
Vapour
Negligible (solid)
Density
No data available (bulk density of lyophilized cake is low)
Solubility
Expected water soluble (PEGylation increases aqueous solubility; the core E-domain 24-mer is water soluble)
Logp
Not applicable (polydisperse conjugate)
Decomp
No data available; peptides decompose above about 200 °C
Other
Core peptide = IGF-1Ec E-domain 24-mer (YQPPSTNKNTKSQRRKGSTFEERK-NH2 type sequence), C121H200N42O39, MW 2867.2; conjugate carries a polydisperse PEG (nominal 2-5 kDa).

10Stability and reactivity

Stability And Reactivity
Reactivity
No dangerous reactions known (generic). PEG chain can autoxidise slowly to peroxides/aldehydes on long air exposure.
Incompatible
Strong oxidizing agents; strong acids/bases.
Decomposition
Carbon oxides, nitrogen oxides on combustion.
Conditions To Avoid
Heat, moisture, light, repeated freeze-thaw; prolonged air exposure of solutions.
Conditions To Avoid
Heat, moisture, light, repeated freeze-thaw; prolonged air exposure of solutions
Incompatible Materials
No data available.

11Toxicological information

Toxicological Information
  • Acute toxicity, oral

    No data available

  • Acute toxicity, dermal

    No data available

  • Acute toxicity, inhalation

    No data available

  • Skin corrosion/irritation

    No data; comparable Cayman peptide SDSs: no irritant effect

  • Serious eye damage/irritation

    No data; comparable Cayman peptide SDSs: no irritating effect

  • Respiratory or skin sensitisation

    No data. Remark: PEG moieties can elicit hypersensitivity (anti-PEG antibodies) in rare individuals.

  • Germ cell mutagenicity

    No data available

  • Carcinogenicity

    Not listed by IARC, NTP, OSHA

  • Reproductive toxicity

    No data available. Growth-factor remark: IGF-1 splice-variant E-domain peptide with mitogenic/growth-factor activity.

  • STOT, single exposure

    No data available

  • STOT, repeated exposure

    No data available

  • Aspiration hazard

    No data available

Routes Of Exposure
Inhalation of dust, skin and eye contact when the vial is opened or the powder is weighed; ingestion through contaminated hands; accidental injection when reconstituted solutions are drawn into syringes.
Symptoms
No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.

12Ecological information

Ecological Information
No data available. By analogy with Cayman peptide SDSs: water hazard class 1 (self-assessment), slightly hazardous for water; PEG moiety biodegrades slowly.

13Disposal considerations

Disposal Guidance
No data available.

14Transport information

Transport Classification
Note
Not regulated as a dangerous good for transport by road (DOT 49 CFR), air (IATA/ICAO) or sea (IMDG). Not a marine pollutant. Ship refrigerated or frozen as required by Section 7; the coolant (dry ice, UN 1845) is regulated when used.

15Regulatory information

Regulatory Information
Tsca
Not listed (no CAS; new conjugate). R&D exemption applies to research use.
Carcinogen Listings
Not listed by IARC, NTP, OSHA, California Prop 65.
Dea
Not a controlled substance.
Other
Not an approved drug. WADA remark: 'Mechano Growth Factors (MGFs)' are explicitly named in WADA Prohibited List S2.2.3 (growth factors and growth factor modulators) - remark only.
Carcinogen Listings
No data available.

16Other information

Revision
October 3, 2026
Sources Consulted
  • No supplier SDS exists for PEG-MGF or for the unmodified MGF E-domain 24-mer from Cayman, .
  • Cayman Chemical - comparable short synthetic peptides
  • Cayman Chemical - IGF-1
Confidence
low
Additional Information
  • Peptide hormone or hormone analogue with potent pharmacological activity at microgram doses. Not classified for reproductive toxicity on the available data, but exposure should be avoided during pregnancy and while nursing as a precaution.
  • No supplier SDS exists; classified by read-across to short synthetic peptides.
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