Safety data sheet. GHS / OSHA HCS 2012 format, 16 sections. Issued by Epic Peptides Lab for the catalogue items listed in Section 1.

Epic Peptides Lab

Safety data sheet · solution, preloaded autoinjector pen

Epic Peptides Lab · USA

Document number: PL-SDS-083
Revision: 1.0 · 2026-10-03

HMG (Menotropins)

solution, preloaded autoinjector pen

1Identification

Product Identifier

HMG (Menotropins)

Document Number

PL-SDS-083

Catalogue Items Covered

Id
20521
Name
Preloaded Autoinjector | hMG (Menotropins) | 3ml Pen | 150IU
Sku
PL-HMG-3ML-PEN

Recommended Use

Laboratory research use by trained personnel.

Restrictions On Use

Not for human or veterinary use.

Supplier / Distributor

Epic Peptides Lab, USA

Telephone

+1 (787) 468-5291

info@epicpeptideslab.com

2Hazard(s) identification

Classification: Not classified as hazardous under OSHA HCS 2012 (29 CFR 1910.1200) or UN GHS, on the basis of the supplier safety data sheets consulted.
Label Elements: No data available.
Signal Word: No data available.
Other Hazards: No data available.

3Composition / information on ingredients

Description

Sterile aqueous solution in bacteriostatic water (0.9% benzyl alcohol), supplied in a 3 mL glass cartridge inside a preloaded autoinjector pen fitted with a needle.

Composition

Name
HMG (Menotropins)
Full
Human menopausal gonadotropin: urinary FSH and LH; potency assigned in IU by bioassay
Cas
61489-71-2
Formula
Not applicable (glycoprotein mixture)
Conc
as labelled (< 10% w/v)
Qty
150 IU per 3 mL pen
Hazards
- Reproductive toxicity — Category 1B — H360
- Specific target organ toxicity, repeated exposure — Category 1 — H372
Name
Benzyl alcohol (preservative)
Full
Benzyl alcohol, antimicrobial preservative (0.9% w/v in bacteriostatic water)
Cas
100-51-6
Formula
C7H8O
Conc
0.9% w/v
Hazards
- Acute toxicity, oral — Category 4 — H302
- Acute toxicity, inhalation — Category 4 — H332
- Serious eye damage/eye irritation — Category 2A — H319
- Skin sensitisation — Category 1B — H317
Name
Water for injection
Full
Water for injection
Cas
7732-18-5
Formula
H2O
Conc
balance to 100%

4First-aid measures

First Aid Measures

Inhalation: Move the person to fresh air and keep comfortable for breathing. If breathing is difficult or symptoms persist, call a POISON CENTER or doctor.
Skin: Take off contaminated clothing. Wash the skin with plenty of soap and water. If irritation or a rash develops, get medical advice.
Eyes: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. If eye irritation persists, get medical advice.
Ingestion: Rinse mouth. Do not induce vomiting. Call a POISON CENTER or doctor if you feel unwell.
Injection: For an accidental needle-stick: wash the site with soap and water, do not squeeze, cover with a dressing and seek medical advice; report the incident according to your laboratory's sharps procedure.

Most Important Symptoms And Effects

No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.

Likely Routes Of Exposure

Accidental needle-stick injection; skin and eye contact from splashes; ingestion is unlikely.

5Fire-fighting measures

Fire Fighting Information: Aqueous solution containing 0.9% benzyl alcohol; not flammable and does not support combustion.

6Accidental release measures

Spill And Clean Up Procedures: Absorb small spills with paper towel or an inert absorbent, place in a sealed container for disposal and clean the area with water and detergent. Pick up broken glass with tongs or forceps, never by hand.

7Handling and storage

Safe Handling: Handle the device as a sharp: never recap or reuse needles, keep fingers away from the needle, and discard used devices into a rigid sharps container. Avoid splashes to eyes and skin. Wash hands after handling.
Safe Storage: Store at 2–8 °C in the original carton, protected from light. Do not freeze; discard if the solution has frozen or is discoloured or cloudy. Once in use, keep the device capped between uses.
Storage Temperature: 2–8 °C, protected from light; do not freeze
Incompatible Materials: Heat and moisture

8Exposure controls / personal protection

Occupational Exposure Limits: Benzyl alcohol: no OSHA PEL, ACGIH TLV or NIOSH REL; AIHA WEEL 10 ppm (44 mg/m³) 8-h TWA. Present at 0.9%.

No occupational exposure limits have been established for the active ingredient(s).
Exposure Controls And PPE: No data available.

9Physical and chemical properties

Physical State

Liquid

Appearance

Clear, colourless to faintly yellow aqueous solution

Properties

Odor: Odourless to faint aromatic odour (benzyl alcohol)
Ph: Approximately 4.5–7.0 (bacteriostatic water, USP) unless adjusted
Melting: About 0 °C (aqueous solution)
Boiling: About 100 °C (aqueous solution)
Flash: Not flammable; aqueous solution (benzyl alcohol flash point 93–101 °C, present at 0.9%)
Vapour: As water (about 2.3 kPa at 20 °C)
Density: About 1.00–1.02 g/mL at 20 °C
Solubility: Aqueous solution; miscible with water
Logp: Not applicable
Decomp: Not applicable (aqueous solution); dissolved peptide degrades on heating

10Stability and reactivity

Stability And Reactivity

Reactivity: Stable under recommended storage and handling temperatures (ProSpec)
Incompatible: Heat and moisture; strong acids/alkalis, strong oxidizing/reducing agents (ProSpec)
Decomposition: In combustion may emit toxic fumes (ProSpec); carbon oxides, nitrogen oxides, sulfur oxides expected
Conditions To Avoid: Heat, moisture, freeze-thaw cycles, dust formation (MSD: gonadotropin powders may form explosive dust-air mixtures during processing)

Conditions To Avoid

Heat, moisture, freeze-thaw cycles, dust formation (MSD: gonadotropin powders may form explosive dust-air mixtures during processing)

Incompatible Materials

Heat and moisture

11Toxicological information

Toxicological Information: Acute toxicity, oral
No data available for hMG. Analogue data: serum gonadotrophin (PMSG) oral LD50 mouse 120 mg/kg (MSD SDS) - analogue only, do not transfer to hMG

Acute toxicity, dermal
No data available

Acute toxicity, inhalation
No data available

Skin corrosion/irritation
Not available (ProSpec). MSD gonadotropin SDS: possible allergic reaction on skin contact

Serious eye damage/irritation
Not available

Respiratory or skin sensitisation
Not available (ProSpec). Human urine-derived glycoprotein - allergic/hypersensitivity reactions are described in the Menopur prescribing information; MSD gonadotropin SDS lists allergic reactions on inhalation

Germ cell mutagenicity
Not available

Carcinogenicity
Not listed by IARC, NTP or OSHA

Reproductive toxicity
Not available (ProSpec). Pharma analogues: Organon recombinant FSH formulation Repr. 1B H360FD (reduced estrous cycles, embryonic resorptions in rats/rabbits); MSD PMSG Repr. 1B H360Fd (LOAEL 10 µg/kg s.c., rat fertility); MSD hCG Repr. 1A (LOAEL 0.224 mg/kg, monkey fertility).

STOT, single exposure
Not available

STOT, repeated exposure
Not available for hMG. Analogues: STOT RE 1 (ovary) H372 for hCG/PMSG and rFSH formulations (MSD, Organon)

Aspiration hazard
Not available
Routes Of Exposure: Accidental needle-stick injection; skin and eye contact from splashes; ingestion is unlikely.
Symptoms: No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.

12Ecological information

Ecological Information: Not available (ProSpec). No ecotoxicity data for gonadotropins in any SDS reviewed; proteins are readily biodegradable in principle.

13Disposal considerations

Disposal Guidance: No data available.

14Transport information

Transport Classification

Note: Not regulated as a dangerous good for transport by road (DOT 49 CFR), air (IATA/ICAO) or sea (IMDG). Not a marine pollutant. Ship refrigerated or frozen as required by Section 7; the coolant (dry ice, UN 1845) is regulated when used.

15Regulatory information

Regulatory Information

Tsca: Not applicable / not listed (ProSpec: TSCA not applicable; biological)
Carcinogen Listings: Not listed by IARC, NTP, OSHA; not Prop 65 listed
Dea: Not a controlled substance (gonadotropins are not DEA-scheduled)
Other: Menotropins is an FDA-approved prescription biologic (Menopur, Ferring; 75 IU FSH / 75 IU LH activity per vial). Human urine-derived: ProSpec product tested negative for HBsAg, anti-HIV and anti-HCV - biological-origin statement belongs in SDS. WADA remark: FSH, LH and hCG are prohibited for males under S2.2 of the WADA Prohibited List.

Carcinogen Listings

No data available.

16Other information

Revision: October 3, 2026
Sources Consulted: ProSpec-Tany TechnoGene

ProSpec product page

Organon

MSD Animal Health

Sigma-Aldrich

Sigma-Aldrich / Supelco

MilliporeSigma

Sigma-Aldrich BVBA

Aldrich

American Regent - Sterile Water for Injection, USP

Hospira/Pfizer - Bacteriostatic Water for Injection
Confidence: medium
Additional Information: Lyophilised recombinant or purified protein. Inhalation of protein dusts can sensitise susceptible individuals; avoid generating dust and handle the dry powder in a ventilated enclosure. Not classified for respiratory sensitisation because no substance-specific data exist.

Derived from animal tissue or human urine. Sourced and processed to minimise adventitious-agent risk; handle with standard biological precautions.

WADA Prohibited List class S2.2.

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