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Safety data sheet. GHS / OSHA HCS 2012 format, 16 sections. Issued by Epic Peptides Lab for the catalogue items listed in Section 1.

Epic Peptides Lab

Safety data sheet · lyophilized powder, vial

Epic Peptides Lab · USA

Document number
PL-SDS-077
Revision
1.0 · 2026-10-03

HCG

lyophilized powder, vial

DANGER

1Identification

Product Identifier
HCG
Document Number
PL-SDS-077
Catalogue Items Covered
  • Id
    2225
    Name
    HCG 10000iu
    Sku
    PL-HCG-10000IU-VIAL
  • Id
    2220
    Name
    HCG 5000iu
    Sku
    PL-HCG-5000IU-VIAL
Recommended Use
Laboratory research use by trained personnel.
Restrictions On Use
Not for human or veterinary use.
Supplier / Distributor
Epic Peptides Lab, USA
Telephone
+1 (787) 468-5291
Email
info@epicpeptideslab.com

2Hazard(s) identification

Classification
  • Reproductive toxicity — Category 1A — H360Fd
  • Specific target organ toxicity, repeated exposure — Category 1 — H372
Label Elements
Pictograms
  • GHS08
Signal
Danger
Hazard statements
  • H360Fd May damage fertility. Suspected of damaging the unborn child.
  • H372 Causes damage to organs (ovary) through prolonged or repeated exposure.
Precautionary statements
  • P201 Obtain special instructions before use.
  • P202 Do not handle until all safety precautions have been read and understood.
  • P260 Do not breathe dust, mist or spray.
  • P264 Wash hands and any exposed skin thoroughly after handling.
  • P270 Do not eat, drink or smoke when using this product.
  • P280 Wear protective gloves, protective clothing and eye protection.
  • P308+P313 IF exposed or concerned: Get medical advice/attention.
  • P314 Get medical advice/attention if you feel unwell.
  • P405 Store locked up.
  • P501 Dispose of contents and container to an approved waste disposal plant in accordance with local, state and federal regulations.
Signal Word
Danger
Other Hazards
No data available.

3Composition / information on ingredients

Description
Lyophilized (freeze-dried) powder or cake in a sealed glass vial with a rubber stopper and aluminium crimp cap.
Composition
  • Name
    HCG
    Full
    Human chorionic gonadotropin (urinary); potency assigned in IU by bioassay
    Cas
    9002-61-3
    Formula
    Not applicable (glycoprotein)
    Conc
    ≥ 95% (dry basis, as supplied)
    Qty
    10000 IU, 5000 IU per vial
    Hazards
    • Reproductive toxicity — Category 1A — H360Fd
    • Specific target organ toxicity, repeated exposure — Category 1 — H372

4First-aid measures

First Aid Measures
Inhalation
Move the person to fresh air and keep comfortable for breathing. If breathing is difficult or symptoms persist, call a POISON CENTER or doctor.
Skin
Take off contaminated clothing. Wash the skin with plenty of soap and water. If irritation or a rash develops, get medical advice.
Eyes
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. If eye irritation persists, get medical advice.
Ingestion
Rinse mouth. Do not induce vomiting. Call a POISON CENTER or doctor if you feel unwell.
General
If exposed or concerned, get medical advice. Show this safety data sheet to the doctor. Pregnant or nursing laboratory staff should avoid exposure.
Most Important Symptoms And Effects
No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.
Likely Routes Of Exposure
Inhalation of dust, skin and eye contact when the vial is opened or the powder is weighed; ingestion through contaminated hands; accidental injection when reconstituted solutions are drawn into syringes.

5Fire-fighting measures

Fire Fighting Information
Combustible organic solid; finely divided powder may form dust clouds. Not flammable in the quantities supplied.

6Accidental release measures

Spill And Clean Up Procedures
Avoid dust formation. Dampen spilled powder with water, wipe up with absorbent material, place in a sealed container for disposal and clean the area with water and detergent.

7Handling and storage

Safe Handling
Open vials only in a clean area. Avoid generating or inhaling dust; weigh or reconstitute inside a ventilated enclosure when the full contents are handled as a dry powder. Reconstitute by adding diluent slowly to the vial wall; do not shake. Wash hands after handling.
Safe Storage
Store the sealed vial at the temperature stated in Section 9 (typically −20 °C for peptides, 2–8 °C for proteins), desiccated and protected from light. Allow the vial to reach room temperature before opening to avoid condensation. Reconstituted solutions: 2–8 °C, protected from light; use within the period established by your laboratory.
Storage Temperature
2–8 °C (sealed vial); −20 °C for long-term storage; protected from light and moisture
Incompatible Materials
Oxidizing agents (Merck/Organon)

8Exposure controls / personal protection

Occupational Exposure Limits
No data available.
Exposure Controls And PPE
No data available.

9Physical and chemical properties

Physical State
Solid
Appearance
White to off-white lyophilized powder or cake
Properties
Odor
Odorless
Ph
Not applicable (solid); aqueous solutions typically pH 4–7
Melting
Not applicable (glycoprotein)
Boiling
Not applicable
Flash
Not applicable (non-flammable solid); combustible organic material
Vapour
Negligible (solid)
Density
No data available (bulk density of lyophilized cake is low)
Solubility
Soluble in water (Sigma CG10: 10 mL water per 10,000 IU vial gives clear to slightly hazy colorless solution)
Logp
Not applicable
Decomp
No data available; peptides decompose above about 200 °C
Other
Heterodimeric glycoprotein, ~36-38 kDa (Sigma quotes 37.9 kDa); ~30% carbohydrate; Merck/Organon: may form explosive dust-air mixture during processing; potency assigned in IU by bioassay

10Stability and reactivity

Stability And Reactivity
Reactivity
Stable under normal conditions; not a reactivity hazard
Incompatible
Oxidizing agents (Merck/Organon)
Decomposition
No hazardous decomposition products identified; thermal decomposition of protein yields carbon oxides and nitrogen oxides
Conditions To Avoid
Heat, moisture, dust formation (explosive dust-air mixture possible), freezing of lyophilized product per BBI ('do not freeze'); store 2-8 C protected from light
Conditions To Avoid
No data available.
Incompatible Materials
No data available.

11Toxicological information

Toxicological Information
  • Acute toxicity, oral

    No data available (not classified for acute toxicity; BBI: 'may be harmful if swallowed' - no value). Note: orally inactive glycoprotein hormone

  • Acute toxicity, dermal

    No data available

  • Acute toxicity, inhalation

    No data available

  • Skin corrosion/irritation

    Not classified; BBI notes possible mild skin irritation

  • Serious eye damage/irritation

    Not classified; BBI notes possible eye irritation/redness

  • Respiratory or skin sensitisation

    Not classified by suppliers (urinary-derived protein - potential sensitiser, see notes)

  • Germ cell mutagenicity

    Not classified; no data

  • Carcinogenicity

    Not classified; not listed by IARC, NTP or OSHA

  • Reproductive toxicity

    Repr. 1A (Merck/Organon): positive evidence from human epidemiological data; animal studies show embryo-fetal toxicity (hamster 60 mg/kg) and fertility effects (primate LOAEL 0.224 mg/kg)

  • STOT, single exposure

    No data available

  • STOT, repeated exposure

    STOT RE 1 - ovary (ovarian hyperstimulation, ovarian cysts/damage on repeated exposure)

  • Aspiration hazard

    No data available

Routes Of Exposure
Inhalation of dust, skin and eye contact when the vial is opened or the powder is weighed; ingestion through contaminated hands; accidental injection when reconstituted solutions are drawn into syringes.
Symptoms
No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.

12Ecological information

Ecological Information
No data available (Merck/Organon: ecotoxicity, persistence, bioaccumulation and mobility all 'no data available'). Protein; expected biodegradable.

13Disposal considerations

Disposal Guidance
No data available.

14Transport information

Transport Classification
Note
Not regulated as a dangerous good for transport by road (DOT 49 CFR), air (IATA/ICAO) or sea (IMDG). Not a marine pollutant. Ship refrigerated or frozen as required by Section 7; the coolant (dry ice, UN 1845) is regulated when used.

15Regulatory information

Regulatory Information
Tsca
Not listed (biologic/glycoprotein; inventory status 'not determined' on Merck/Organon SDS)
Carcinogen Listings
Not listed by IARC, NTP, OSHA, EPA
Dea
Not a federally controlled substance in the US (prescription biologic). UK: Misuse of Drugs Regulations 2001 Schedule 4 Part 2 controlled drug (BBI SDS)
Other
WADA Prohibited List S2.2 - chorionic gonadotropin prohibited in males (remark only). FDA-approved drug (Novarel, Pregnyl); urinary-derived human biologic - donor screening/handling as potentially infectious material of human origin is a reasonable precaution.
Carcinogen Listings
No data available.

16Other information

Revision
October 3, 2026
Sources Consulted
  • Merck Animal Health
  • Organon
  • MSD Animal Health
  • BBI Solutions
Confidence
high
Additional Information
  • Lyophilised recombinant or purified protein. Inhalation of protein dusts can sensitise susceptible individuals; avoid generating dust and handle the dry powder in a ventilated enclosure. Not classified for respiratory sensitisation because no substance-specific data exist.
  • Derived from animal tissue or human urine. Sourced and processed to minimise adventitious-agent risk; handle with standard biological precautions.
  • WADA Prohibited List class S2 (prohibited for males).
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