Safety data sheet. GHS / OSHA HCS 2012 format, 16 sections. Issued by Epic Peptides Lab for the catalogue items listed in Section 1.

Epic Peptides Lab

Safety data sheet · solution, metered nasal spray

Epic Peptides Lab · USA

Document number
PL-SDS-017
Revision
1.0 · 2026-10-03

ARA-290

solution, metered nasal spray

1Identification

Product Identifier
ARA-290
Document Number
PL-SDS-017
Catalogue Items Covered
  • Id
    15815
    Name
    ARA-290 10mg Nasal Spray
    Sku
    PL-ARA290-10MG-NS
Recommended Use
Laboratory research use by trained personnel.
Restrictions On Use
Not for human or veterinary use.
Supplier / Distributor
Epic Peptides Lab, USA
Telephone
+1 (787) 468-5291
Email
info@epicpeptideslab.com

2Hazard(s) identification

Classification
Not classified as hazardous under OSHA HCS 2012 (29 CFR 1910.1200) or UN GHS, on the basis of the supplier safety data sheets consulted.
Label Elements
No data available.
Signal Word
No data available.
Other Hazards
No data available.

3Composition / information on ingredients

Description
Sterile aqueous solution in bacteriostatic water (0.9% benzyl alcohol), supplied in a metered-dose nasal spray bottle.
Composition
  • Name
    ARA-290
    Full
    Cibinetide; erythropoietin helix-B surface peptide
    Cas
    1208243-50-8
    Formula
    C51H84N16O21
    Conc
    ≤ 0.1% w/v
    Qty
    10 mg per bottle
  • Name
    Benzyl alcohol (preservative)
    Full
    Benzyl alcohol, antimicrobial preservative (0.9% w/v in bacteriostatic water)
    Cas
    100-51-6
    Formula
    C7H8O
    Conc
    0.9% w/v
    Hazards
    • Acute toxicity, oral — Category 4 — H302
    • Acute toxicity, inhalation — Category 4 — H332
    • Serious eye damage/eye irritation — Category 2A — H319
    • Skin sensitisation — Category 1B — H317
  • Name
    Water for injection
    Full
    Water for injection
    Cas
    7732-18-5
    Formula
    H2O
    Conc
    balance to 100%

4First-aid measures

First Aid Measures
Inhalation
Move the person to fresh air and keep comfortable for breathing. If breathing is difficult or symptoms persist, call a POISON CENTER or doctor.
Skin
Take off contaminated clothing. Wash the skin with plenty of soap and water. If irritation or a rash develops, get medical advice.
Eyes
Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. If eye irritation persists, get medical advice.
Ingestion
Rinse mouth. Do not induce vomiting. Call a POISON CENTER or doctor if you feel unwell.
Injection
For an accidental needle-stick: wash the site with soap and water, do not squeeze, cover with a dressing and seek medical advice; report the incident according to your laboratory's sharps procedure.
Most Important Symptoms And Effects
No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.
Likely Routes Of Exposure
Inhalation of the aerosol and absorption through the nasal mucosa are the intended laboratory routes; eye contact from mis-directed spray; skin contact.

5Fire-fighting measures

Fire Fighting Information
Aqueous solution containing 0.9% benzyl alcohol; not flammable and does not support combustion.

6Accidental release measures

Spill And Clean Up Procedures
Absorb small spills with paper towel or an inert absorbent, place in a sealed container for disposal and clean the area with water and detergent.

7Handling and storage

Safe Handling
Avoid spraying toward the eyes or face. Do not share devices. Wipe the nozzle after use and keep the cap on. Wash hands after handling.
Safe Storage
Store at 2–8 °C, protected from light; do not freeze. Keep upright and capped.
Storage Temperature
2–8 °C, protected from light; do not freeze
Incompatible Materials
None specified by supplier

8Exposure controls / personal protection

Occupational Exposure Limits
  • Benzyl alcohol: no OSHA PEL, ACGIH TLV or NIOSH REL; AIHA WEEL 10 ppm (44 mg/m³) 8-h TWA. Present at 0.9%.
  • No occupational exposure limits have been established for the active ingredient(s).
Exposure Controls And PPE
No data available.

9Physical and chemical properties

Physical State
Liquid
Appearance
Clear, colourless to faintly yellow aqueous solution
Properties
Odor
Odourless to faint aromatic odour (benzyl alcohol)
Ph
Approximately 4.5–7.0 (bacteriostatic water, USP) unless adjusted
Melting
About 0 °C (aqueous solution)
Boiling
About 100 °C (aqueous solution)
Flash
Not flammable; aqueous solution (benzyl alcohol flash point 93–101 °C, present at 0.9%)
Vapour
As water (about 2.3 kPa at 20 °C)
Density
About 1.00–1.02 g/mL at 20 °C
Solubility
Aqueous solution; miscible with water
Logp
Not determined
Decomp
Not applicable (aqueous solution); dissolved peptide degrades on heating

10Stability and reactivity

Stability And Reactivity
Reactivity
No hazardous reactions known; stable when stored and handled per specifications
Incompatible
None specified by supplier (generic for peptides: strong oxidizing agents, strong acids/bases)
Decomposition
No dangerous decomposition products known (combustion would give carbon oxides and nitrogen oxides)
Conditions To Avoid
None specified; store at -20 C, desiccated, protected from light; avoid repeated freeze-thaw
Conditions To Avoid
None specified; store at -20 C, desiccated, protected from light; avoid repeated freeze-thaw
Incompatible Materials
None specified by supplier

11Toxicological information

Toxicological Information
  • Acute toxicity, oral

    No data available

  • Acute toxicity, dermal

    No data available

  • Acute toxicity, inhalation

    No data available

  • Skin corrosion/irritation

    No irritant effect (Cayman)

  • Serious eye damage/irritation

    No irritating effect (Cayman)

  • Respiratory or skin sensitisation

    No sensitizing effects known

  • Germ cell mutagenicity

    No data available

  • Carcinogenicity

    Not listed by IARC, NTP or OSHA

  • Reproductive toxicity

    No data available; not listed

  • STOT, single exposure

    No data available

  • STOT, repeated exposure

    No data available

  • Aspiration hazard

    No data available

Routes Of Exposure
Inhalation of the aerosol and absorption through the nasal mucosa are the intended laboratory routes; eye contact from mis-directed spray; skin contact.
Symptoms
No specific symptoms are known. Pharmacologically active material: systemic effects consistent with its mechanism of action are possible after accidental injection, ingestion or absorption.

12Ecological information

Ecological Information
No aquatic toxicity, persistence or bioaccumulation data available. Cayman self-assessment: water hazard class 1 (slightly hazardous for water); do not discharge to groundwater or drains. PBT/vPvB not applicable.

13Disposal considerations

Disposal Guidance
No data available.

14Transport information

Transport Classification
Note
Not regulated as a dangerous good for transport by road (DOT 49 CFR), air (IATA/ICAO) or sea (IMDG). Not a marine pollutant. Ship refrigerated or frozen as required by Section 7; the coolant (dry ice, UN 1845) is regulated when used.

15Regulatory information

Regulatory Information
Tsca
Not listed on TSCA inventory (Cayman)
Carcinogen Listings
Not listed by IARC, NTP, OSHA or EPA
Dea
Not a controlled substance
Other
SARA 313: not listed. Transport: not regulated (DOT/IMDG/IATA). WADA remark: ARA-290 is an erythropoietin-derived peptide (helix-B surface peptide) that does not bind the classical EPO receptor; it is not specifically named on the WADA Prohibited List but authors may note WADA S2.1 (agents affecting erythropoiesis) as a remark only.
Carcinogen Listings
No data available.

16Other information

Revision
October 3, 2026
Sources Consulted
  • Cayman Chemical
  • ChemicalBook
  • Sigma-Aldrich
  • Sigma-Aldrich / Supelco
  • MilliporeSigma
  • Sigma-Aldrich BVBA
  • Aldrich
  • American Regent - Sterile Water for Injection, USP
  • Hospira/Pfizer - Bacteriostatic Water for Injection
Confidence
high
Additional Information
  • Concentrations are calculated for a nominal 10 mL bottle fill, the smallest fill PrymaLab supplies; larger fills give lower concentrations and the same or a less severe classification.
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