Safety data sheet. GHS / OSHA HCS 2012 format, 16 sections. Issued by Epic Peptides Lab for the catalogue items listed in Section 1.

Epic Peptides Lab

Safety data sheet · lyophilized powder, vial

Epic Peptides Lab · USA

Document number: PL-SDS-009
Revision: 1.0 · 2026-10-03

AICAR

lyophilized powder, vial

WARNING

1Identification

Product Identifier

AICAR

Document Number

PL-SDS-009

Catalogue Items Covered

Id
2822
Name
AICAR 50MG
Sku
PL-AICAR-50MG-VIAL

Recommended Use

Laboratory research use by trained personnel.

Restrictions On Use

Not for human or veterinary use.

Supplier / Distributor

Epic Peptides Lab, USA

Telephone

+1 (787) 468-5291

info@epicpeptideslab.com

2Hazard(s) identification

Classification

Skin corrosion/irritation — Category 2 — H315
Serious eye damage/eye irritation — Category 2A — H319
Specific target organ toxicity, single exposure (respiratory tract irritation) — Category 3 — H335

Label Elements

Pictograms: GHS07
Signal: Warning
Hazard statements: H315 Causes skin irritation.

H319 Causes serious eye irritation.

H335 May cause respiratory irritation.
Precautionary statements: P261 Avoid breathing dust, mist or spray.

P264 Wash hands and any exposed skin thoroughly after handling.

P271 Use only outdoors or in a well-ventilated area.

P280 Wear protective gloves, protective clothing and eye protection.

P302+P352 IF ON SKIN: Wash with plenty of water.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P312 Call a POISON CENTER or doctor if you feel unwell.

P321 Specific treatment: see Section 4 of this safety data sheet.

P332+P313 If skin irritation occurs: Get medical advice/attention.

P337+P313 If eye irritation persists: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

P501 Dispose of contents and container to an approved waste disposal plant in accordance with local, state and federal regulations.

Signal Word

Warning

Other Hazards

No data available.

3Composition / information on ingredients

Description

Lyophilized (freeze-dried) powder or cake in a sealed glass vial with a rubber stopper and aluminium crimp cap.

Composition

Name
AICAR
Full
Acadesine; 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; nucleoside, not a peptide
Cas
2627-69-2
Formula
C9H14N4O5
Conc
≥ 95% (dry basis, as supplied)
Qty
50 mg per vial
Hazards
- Skin corrosion/irritation — Category 2 — H315
- Serious eye damage/eye irritation — Category 2A — H319
- Specific target organ toxicity, single exposure (respiratory tract irritation) — Category 3 — H335

4First-aid measures

First Aid Measures

Inhalation: Move the person to fresh air and keep comfortable for breathing. If breathing is difficult or symptoms persist, call a POISON CENTER or doctor.
Skin: Take off contaminated clothing. Wash the skin with plenty of soap and water. If irritation or a rash develops, get medical advice.
Eyes: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. If eye irritation persists, get medical advice.
Ingestion: Rinse mouth. Do not induce vomiting. Call a POISON CENTER or doctor if you feel unwell.

Most Important Symptoms And Effects

skin redness or irritation; eye redness, watering and irritation; coughing and irritation of the nose and throat after inhaling dust.

Likely Routes Of Exposure

Inhalation of dust, skin and eye contact when the vial is opened or the powder is weighed; ingestion through contaminated hands; accidental injection when reconstituted solutions are drawn into syringes.

5Fire-fighting measures

Fire Fighting Information: Combustible organic solid; finely divided powder may form dust clouds. Not flammable in the quantities supplied.

6Accidental release measures

Spill And Clean Up Procedures: Avoid dust formation. Dampen spilled powder with water, wipe up with absorbent material, place in a sealed container for disposal and clean the area with water and detergent.

7Handling and storage

Safe Handling: Open vials only in a clean area. Avoid generating or inhaling dust; weigh or reconstitute inside a ventilated enclosure when the full contents are handled as a dry powder. Reconstitute by adding diluent slowly to the vial wall; do not shake. Wash hands after handling.
Safe Storage: Store the sealed vial at the temperature stated in Section 9 (typically −20 °C for peptides, 2–8 °C for proteins), desiccated and protected from light. Allow the vial to reach room temperature before opening to avoid condensation. Reconstituted solutions: 2–8 °C, protected from light; use within the period established by your laboratory.
Storage Temperature: −20 °C (sealed vial), desiccated and protected from light; 2–8 °C acceptable for short periods
Incompatible Materials: Strong oxidizing agents

8Exposure controls / personal protection

Occupational Exposure Limits: No data available.
Exposure Controls And PPE: No data available.

9Physical and chemical properties

Physical State

Solid

Appearance

White to off-white crystalline powder

Properties

Odor: Characteristic (Cayman); odor threshold not determined
Ph: Not applicable (solid); aqueous solutions typically pH 4–7
Melting: 212 °C (TCI); 214-215 °C (ChemicalBook); Cayman: undetermined
Boiling: Undetermined
Flash: Not applicable (non-flammable solid); combustible organic material
Vapour: Negligible (solid)
Density: No data available (bulk density of lyophilized cake is low)
Solubility: Cayman: DMF 10 mg/ml; DMSO 20 mg/ml; ethanol 1 mg/ml; PBS pH 7.2 2.5 mg/ml. ChemicalBook: water >10 mg/ml
Logp: No data available
Decomp: No data available; peptides decompose above about 200 °C
Other: Not flammable (Cayman). Specific rotation -61.0 to -66.0° (c=1, H2O) (TCI). Heat sensitive; store frozen (TCI). MW 258.2, C9H14N4O5

10Stability and reactivity

Stability And Reactivity

Reactivity: No dangerous reactions known; no decomposition if used according to specifications (Cayman). Chemically stable at room temperature (ChemicalBook)
Incompatible: Strong oxidizing agents
Decomposition: Carbon oxides, nitrogen oxides
Conditions To Avoid: Heat (heat sensitive per TCI, store frozen); dust formation (potential dust explosion hazard if finely dispersed, ChemicalBook)

Conditions To Avoid

Heat (heat sensitive per TCI, store frozen); dust formation (potential dust explosion hazard if finely dispersed, ChemicalBook)

Incompatible Materials

No data available.

11Toxicological information

Toxicological Information: Acute toxicity, oral
No data available (no LD50 in Cayman, TCI or ChemicalBook SDS)

Acute toxicity, dermal
No data available

Acute toxicity, inhalation
No data available

Skin corrosion/irritation
Irritant to skin and mucous membranes (Cayman); classified Skin Irrit. 2

Serious eye damage/irritation
Irritating effect (Cayman); classified Eye Irrit. 2A

Respiratory or skin sensitisation
No sensitizing effects known (Cayman)

Germ cell mutagenicity
No data available

Carcinogenicity
Not listed by IARC, NTP or OSHA (Cayman)

Reproductive toxicity
No data available

STOT, single exposure
May cause respiratory irritation (Category 3) per Cayman and ChemicalBook; TCI does not carry H335

STOT, repeated exposure
No data available

Aspiration hazard
No data available
Routes Of Exposure: Inhalation of dust, skin and eye contact when the vial is opened or the powder is weighed; ingestion through contaminated hands; accidental injection when reconstituted solutions are drawn into syringes.
Symptoms: skin redness or irritation; eye redness, watering and irritation; coughing and irritation of the nose and throat after inhaling dust.

12Ecological information

Ecological Information: Cayman: Water hazard class 1 (self-assessment), slightly hazardous for water; no aquatic toxicity, persistence or bioaccumulation data available. Do not allow undiluted product to reach ground water or sewage.

13Disposal considerations

Disposal Guidance: No data available.

14Transport information

Transport Classification

Note: Not regulated as a dangerous good for transport by road (DOT 49 CFR), air (IATA/ICAO) or sea (IMDG). Not a marine pollutant. Ship refrigerated or frozen as required by Section 7; the coolant (dry ice, UN 1845) is regulated when used.

15Regulatory information

Regulatory Information

Tsca: Listed, ACTIVE (Cayman, ChemicalBook)
Carcinogen Listings: Not listed by IARC, NTP, OSHA, ACGIH, EPA or NIOSH-Ca; not Prop 65 listed
Dea: Not a controlled substance
Other: Not listed under SARA 302/313 or as a HAP (Cayman). Listed on EINECS (ChemicalBook). WADA remark: AICAR is explicitly named on the WADA Prohibited List (S4.4 Metabolic modulators, AMPK activators) - verify current list year.

Carcinogen Listings

No data available.

16Other information

Revision: October 3, 2026
Sources Consulted: Cayman Chemical

TCI

ChemicalBook
Confidence: high
Additional Information: WADA Prohibited List class S4.4 (metabolic modulators).

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